5F-MDMB-2201

Introduction to 5F-MDMB-2201

5F-MDMB-2201 is a synthetic cannabinoid belonging to the indazole family. It is structurally similar to MMB-2201 and acts as a potent agonist at both cannabinoid receptors CB1 and CB2. This compound is primarily studied in research settings for its chemical structure and receptor interactions.

Chemical Structure and Properties

The systematic chemical name of 5F-MDMB is:
methyl 2-(1-(5-fluoropentyl)-1H-indole-3-carboxamido)-3,3-dimethylbutanoate

• CAS Number: 889493-21-2
• Molecular Formula: C21H29FN2O3
• Molecular Weight: 376.49 g/mol
• Purity: ≥ 99.7%
• Appearance: Crystalline solid

5F-MDMB features a 5-fluoropentyl chain on the indole ring and a dimethylbutanoate ester, contributing to its potent activity at cannabinoid receptors.

Research Context

Synthetic cannabinoids like 5F-MDMB are studied in laboratory and pharmacological research to understand:

• Binding affinity and activity at CB1 and CB2 receptors
• Structure-activity relationships (SAR) in indazole cannabinoids
• Molecular pharmacology and chemical interactions

Physiological, toxicological, and long-term effects of 5F-MDMB-2201 remain largely unstudied, highlighting the importance of controlled research environments.

Handling and Safety Considerations

5F-MDMB should only be handled in controlled laboratory settings. Researchers must follow strict safety protocols, use personal protective equipment (PPE), and comply with local regulations, as its pharmacological and toxicological profiles are not fully characterized.

Summary

5F-MDMB-2201 is a high-purity, indazole-based synthetic cannabinoid used in research to study receptor activity, chemical interactions, and structure-activity relationships. Its potency at CB1 and CB2 receptors makes it a significant compound for laboratory studies in cannabinoid pharmacology.