SGT-263

SGT-263, also known as CUMYL-5F-P7AICA or 5F-CUMYL-P7AICA, is a potent synthetic cannabinoid belonging to the pyrrolo[2,3-b]pyridine-3-carboxamide class. It exhibits effects similar to MMB-CHMINACA and has been identified by the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA).

Chemical Structure and Properties

The IUPAC name of SGT-263 is:
1-(5-fluoropentyl)-N-(2-phenylpropan-2-yl)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide

• Molecular Formula: C22H26FN3O
• Molecular Weight: 367.47 g/mol
• Purity: ≥ 99.7%
• Appearance: Crystalline solid

SGT-263 features a 5-fluoropentyl side chain and a pyrrolo[2,3-b]pyridine core, contributing to its potent activity at cannabinoid receptors.

Research Context

Synthetic cannabinoids like SGT-263 are primarily studied in laboratory and pharmacological research to explore:

• Binding and agonist activity at CB1 and CB2 receptors
• Structure-activity relationships (SAR) in pyrrolo[2,3-b]pyridine-based cannabinoids
• Molecular pharmacology and chemical behavior

Current data on physiological and toxicological effects are limited, making controlled research environments essential for safety.

Handling and Safety Considerations

SGT-263 should only be handled in controlled laboratory settings. Researchers must use proper personal protective equipment (PPE) and adhere to safety protocols, as the compound’s pharmacological and toxicological profiles are not fully characterized.

Summary

SGT (CUMYL-5F-P7AICA) is a high-purity pyrrolo[2,3-b]pyridine-based synthetic cannabinoid studied for receptor activity, molecular interactions, and structure-activity relationships. Its potency and structural similarity to other cannabinoids make it significant in cannabinoid research.